Claudia Istrate

 

Biography

Claudia Istrate (DVM, PhD)

In 2001, I got my degree in Veterinary Medicine (DVM) awarded by the Faculty of Veterinary Medicine of Cluj-Napoca, Romania and in 2007, the PhD degree from NOVA University of Lisbon, Portugal. The main goals of the PhD project were to produce/purify a rotavirus (RV) subunit vaccine candidate, to test the efficacy of this vaccine in different animal models (infant and adult mice, gnotobiotic pigs) and to look into the pathophysiological mechanisms of the RV disease (in vitro and in vivo). Afterwards, studies on pathophysiological mechanisms were continued during two postdoc periods (2007-2008 and 2018) at Prof. Lennart Svensson´s lab, at Linköping University, in Sweden.

Between 2008-2015, at the Institute of Hygiene and Tropical Medicine (IHTM), in Lisbon, Portugal, my research objectives became oriented towards translational and applied research in low and middle-income countries and Portugal. I investigated the molecular epidemiology of viruses (rota-, noro-, astro- and adenovirus) causing acute gastroenteritis in children under five years of age and the host genetic factors associated to these viruses. Research results were published in fifteen peer reviewed papers, two book chapters and three papers in non-SCI journals (from Portugal and Angola). Research results were presented at about 50 national and international conferences. Presently I collaborate with the Global Health and Tropical Medicine research center from IHTM in Lisbon, Portugal.